Radiation Therapy Treatment Options

Our national network of radiation therapy centers offers a variety of highly advanced cancer treatment options for different forms and stages of cancer. In this section, read about the various cancer treatment approaches and learn which might be right for you. Or, use our location finder to see which of our centers and treatment options are available near you.

External Beam Radiation Therapy (EBRT)

EBRT uses highly sophisticated systems to irradiate tumors from outside the body. It is a powerful weapon against many different types of cancer. In some cases EBRT is applied as a standalone radiation therapy. In others, it is recommended either before or after surgery.

If you and your 21st Century Oncology team decide on EBRT, there are several different technology options available.

EBRT technology options

  • 3D-Conformal Radiation Therapy, which conforms the radiation beam to the shape of the tumor
  • Intensity-Modulated Radiation Therapy, which precisely adjusts the strength of thousands of individual "beamlets" aimed at the tumor
  • Tomotherapy
  • Stereotactic Radiosurgery
  • Stereotactic Body Radiotherapy

All of these systems use Image Guided Radiation Therapy (IGRT) to ensure proper patient positioning. Some also feature real-time tumor tracking called respiratory gating, where the radiation beams are continuously adjusted to accommodate the motion of the patient’s breathing. This means that radiation only hits the tumor and not the healthy tissue surrounding it.

While these different therapies may share similar features and benefits, each is particularly effective against or suitable for certain tumors. Talk to your doctor about which one might be right for you.


Brachytherapy is a powerful form of radiation therapy that destroys a number of different types of cancers including prostate, gynecologic and breast cancer. It can be used as a standalone cancer treatment or after a tumor has been surgically removed to eliminate any remaining cancerous cells and help prevent a recurrence.

There are two types of Brachytherapy: High-Dose Rate (HDR) and Low-Dose Rate (LDR). The difference is the rate at which the radiation is delivered.

Brachytherapy targets tumors with radiation delivered through a catheter. Since the radiation does not pass through healthy tissue to treat the tumor, it is extremely precise and enables your Radiation Oncologist to target the radiation directly at the tumor site with less risk of damage to surrounding healthy tissue.

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